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Article

STXBP1 as a therapeutic target for epileptic encephalopathy.

Expert opinion on therapeutic targets - 1 Nov 2017

Stamberger Hannah, Weckhuysen Sarah, De Jonghe Peter

Abstract excerpt

INTRODUCTION: STXBP1 is an essential protein for presynaptic vesicle release. Mutations in STXBP1 have been associated with a series of (epileptic) neurodevelopmental disorders collectively referred to as STXBP1-encephalopathy (STXBP1-E). In this review we hypothesize about the potential of STXBP1 as a therapeutic target in the field of epileptic encephalopathies. Areas covered: A state of the art overview on...

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Source

Identifiers

PMID: 28971703
DOI: 10.1080/14728222.2017.1386175

Genes

STXBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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