Gefitinib Plus Chemotherapy Versus Chemotherapy in Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer Resistant to First-Line Gefitinib (IMPRESS): Overall Survival and Biomarker Analyses.

doi:10.1200/JCO.2017.73.9250

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Gefitinib Plus Chemotherapy Versus Chemotherapy in Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer Resistant to First-Line Gefitinib (IMPRESS): Overall Survival and Biomarker Analyses.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Dec 2017

Mok Tony S K, Kim Sang-We, Wu Yi-Long, Nakagawa Kazuhiko, Yang Jin-Ji, Ahn Myung-Ju, Wang Jie, Yang James Chih-Hsin, Lu You, Atagi Shinji, Ponce Santiago, Shi Xiaojin, Rukazenkov Yuri, Haddad Vincent, Thress Kenneth S, Soria Jean-Charles

Abstract excerpt

Purpose The Iressa Mutation-Positive Multicentre Treatment Beyond ProgRESsion Study (IMPRESS) compared the continuation of gefitinib plus chemotherapy with placebo plus chemotherapy in patients with epidermal growth factor receptor ( EGFR) mutation-positive advanced non-small-cell lung cancer with progression (Response Evaluation Criteria in Solid Tumors 1.1) after first-line gefitinib. Primary results indicated...

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PMID: 28968167
DOI: 10.1200/JCO.2017.73.9250

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