Article
Meta-analysis of first-line therapies with maintenance regimens for advanced non-small-cell lung cancer (NSCLC) in molecularly and clinically selected populations.
Cancer medicine - 1 Aug 2017
Tan Pui San, Bilger Marcel, de Lima Lopes Gilberto, Acharyya Sanchalika, Haaland Benjamin
Abstract excerpt
Evidence has suggested survival benefits of maintenance for advanced NSCLC patients not progressing after first-line chemotherapy. Additionally, particular first-line targeted therapies have shown survival improvements in selected populations. Optimal first-line and maintenance therapies remain unclear. Here, currently available evidence was synthesized to elucidate optimal first-line and maintenance therapy...
Topics
- Antineoplastic Combined Chemotherapy Protocols
- Bayes Theorem
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Genes, erbB-1
- Humans
- Induction Chemotherapy
- Lung Neoplasms
- Maintenance Chemotherapy
- Mutation
- Neoplasm Metastasis
- Neoplasm Staging