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Hypermethylated ZNF582 and PAX1 genes in mouth rinse samples as biomarkers for oral dysplasia and oral cancer detection

27 Sept 2017

Abstract excerpt

Abstract Background Effective biomarkers for oral cancer screening are important for early diagnosis and treatment of oral cancer. Methods Oral epithelial cell samples collected by mouth rinse were obtained from 65 normal control subjects, 108 patients with oral potentially malignant disorders, and 94 patients with oral squamous cell carcinoma (OSCC). Methylation levels of zinc‐finger protein 582 (ZNF582) and...

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PMID: 28960639
DOI: 10.1002/hed.24958

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