Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Triggering p53 activation is essential in ziyuglycoside I‐induced human retinoblastoma WERI‐Rb‐1 cell apoptosis

28 Sept 2017

Abstract excerpt

Ziyuglycoside I (Ziyu I), one of the major components isolated from the root of Sanguisorba officinalis L., has been proved for the antitumor properties on oral cancer, prostate cancer, and colorectal cancer. However, the effect of Ziyu I on retinoblastoma (RB) is not well understood. In this study, we investigated the inhibitory effect and underlying molecular mechanism of Ziyu I on human RB WERI-Rb-1 cells. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28960612
DOI: 10.1002/jbt.22001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Triggering p53 activation is essential in ziyuglycoside I‐induced human retinoblastoma WERI‐Rb‐1 cell apoptosisPMID 28960612Read ↗

Salidroside induces apoptosis in human ovarian cancer SKOV3 and A2780 cells through the p53 signaling pathwaySemantic proximity Read ↗

Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancerSemantic proximity Read ↗

Selective Killing of Cancer Cells by Leaf Extract of Ashwagandha: Identification of a Tumor-Inhibitory Factor and the First Molecular Insights to Its EffectSemantic proximity Read ↗

Targeting the RB-pathway in Cancer TherapySemantic proximity Read ↗

Crocin inhibits proliferation and induces apoptosis through suppressing MYCN expression in retinoblastomaSemantic proximity Read ↗

Theabrownin triggers DNA damage to suppress human osteosarcoma U2 OS cells by activating p53 signalling pathwaySemantic proximity Read ↗

Volatile Oil of Acori Graminei Rhizoma-Induced Apoptosis and Autophagy are dependent on p53 Status in Human Glioma Cells.Semantic proximity Read ↗

Anticancer effects of salvianolic acid A through multiple signaling pathways (Review)Semantic proximity Read ↗

Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cellsSemantic proximity Read ↗

Guilu erxian glue alleviates chemotherapy-induced myelosuppression by regulating histone methylation level of p16 gene in hematopoietic stem cellsSemantic proximity Read ↗

Effect of piceatannol-rich passion fruit seed extract on human glyoxalase I–mediated cancer cell growthSemantic proximity Read ↗

Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In VivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.