Article
Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner.
Journal of virology - 1 Dec 2017
Li Zi, Zhao Kui, Lan Yungang, Lv Xiaoling, Hu Shiyu, Guan Jiyu, Lu Huijun, Zhang Jing, Shi Junchao, Yang Yawen, Song Deguang, Gao Feng, He Wenqi
Abstract excerpt
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a highly neurovirulent coronavirus that invades the central nervous system (CNS) in piglets. Although important progress has been made toward understanding the biology of PHEV, many aspects of its life cycle remain obscure. Here we dissected the molecular mechanism underlying cellular entry and intracellular trafficking of PHEV in mouse neuroblastoma...
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