Article
Urinary cell-free DNA as a prognostic marker for KRAS-positive advanced-stage NSCLC.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 May 2018
Xie F, Li P, Gong J, Tan H, Ma J
Abstract excerpt
BACKGROUND: KRAS mutations are prevalent in non-small cell lung cancer (NSCLC) but its clinical implications remain to be determined. Continual profiling of KRAS mutations in patients is challenging, and the study aims to determine the potential use of urinary DNA in disease predictions. METHODS: A total of 150 patients were recruited. To ascertain the clinical relevance of urinary DNA, matched tumor profiles...
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