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Article

Association of Heparin-binding EGF-like Growth Factor Polymorphisms With Necrotizing Enterocolitis in Preterm Infants.

Journal of pediatric gastroenterology and nutrition - 1 Apr 2018

Ma Fei, Li Sitao, Hao Hu, Gao Pingmin, Dai Yiheng, Himani Chhetri, Liu Weidong, Gao Xiaoyan, Xiao Xin

Abstract excerpt

Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) protects the intestines from injury in experimental necrotizing enterocolitis (NEC). We hypothesized that polymorphisms in the HB-EGF gene lead to low HB-EGF production in peripheral blood and increased risk of NEC in the Chinese Han population. To test this hypothesis, 30 NEC patients and 80 control subjects were selected. Five HB-EGF...

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Source

Identifiers

PMID: 28953531
DOI: 10.1097/MPG.0000000000001753

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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