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Article

Attenuation of antimicrobial activity by the human steroid hormones.

Steroids - 1 Dec 2017

Plotkin Balbina J, Konakieva Monika I

Abstract excerpt

Upon entering the human host, Staphylococcus aureus is exposed to endogenous steroid hormones. The interaction between S. aureus and dehydroepiandosterone (DHEA) results in an increased resistance to the host cationic defense peptide, β-1 defensin, as well as vancomycin and other antibiotics that have a positive charge. The increased resistance to vancomycin is phenotypic and appears to correlate with a...

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Identifiers

PMID: 28951169
DOI: 10.1016/j.steroids.2017.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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