Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cervical cancer screening cotesting with cytology and MRNA HPV E6/E7 yields high rates of CIN2+ lesions in young women.

Diagnostic cytopathology - 1 Dec 2017

Granados Rosario, Tellez-Safina Hilda, Solis Isabel, Mateos Francisco, Rodriguez-Barbero Jose Maria, Aramburu Jose Antonio, Huertas Miguel Angel, Bajo Paloma, Camarmo Encarnacion, Corrales Teresa, Medina Pedro, Calvo Beatriz, Martin Esther, Anta Laura, Zamora Manuel, Alcaide Teresa

Abstract excerpt

BACKGROUND: European guidelines recommend primary HPV testing for cervical cancer screening. However, the starting age remains to be defined, with an undecided window between 30 and 35 years. This pilot study compares the effectiveness of primary HPV testing to that of cytology for the detection of high-grade (CIN2+) lesions stratified by age. METHODS: Cotesting with LBC cytology and APTIMA® HPV (AHPV) was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colposcopy
Share to Cytodiagnosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Mass Screening

Share to Oncogene Proteins, Viral

Share to Papillomaviridae

Share to Pilot Projects

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 28949442
DOI: 10.1002/dc.23821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cervical cancer screening cotesting with cytology and MRNA HPV E6/E7 yields high rates of CIN2+ lesions in young women.PMID 28949442Read ↗

Head-to-Head Comparison of the RNA-Based Aptima Human Papillomavirus (HPV) Assay and the DNA-Based Hybrid Capture 2 HPV Test in a Routine Screening Population of Women Aged 30 to 60 Years in Germany.Semantic proximity Read ↗

Is HPV DNA testing specificity comparable to that of cytological testing in primary cervical cancer screening? Results of a meta‐analysis of randomized controlled trialsSemantic proximity Read ↗

Diagnostic accuracy of high-risk HPV DNA genotyping for primary cervical cancer screening and triage of HPV-positive women, compared to cytology: preliminary results of the PIPAVIR study.Semantic proximity Read ↗

A review of the clinical performance of the Aptima HPV assay.Semantic proximity Read ↗

HPV DNA testing in population-based cervical screening (VUSA-Screen study): results and implicationsSemantic proximity Read ↗

Longitudinal Clinical Performance of the RNA-Based Aptima Human Papillomavirus (AHPV) Assay in Comparison to the DNA-Based Hybrid Capture 2 HPV Test in Two Consecutive Screening Rounds with a 6-Year Interval in GermanySemantic proximity Read ↗

Primary HPV testing verification: A retrospective ad-hoc analysis of screening algorithms on women doubly tested for cytology and HPV.Semantic proximity Read ↗

High prevalence of abnormal cervical smears in a hospital cohort of French women beyond the upper age limit screening program.Semantic proximity Read ↗

Performance of human papillomavirus (HPV) mRNA testing and HPV 16 and 18/45 genotyping combined with age stratification in the triaging of women with ASC-US cytology.Semantic proximity Read ↗

Performance of the HPV E6/E7 mRNA Aptima HPV assay combined with partial genotyping compared with the HPV DNA Cobas 4800 HPV test for use in primary screening: Results from the CERVIVA HPV primary screening study in Ireland.Semantic proximity Read ↗

Validity of combined cytology and human papillomavirus (HPV) genotyping with adjuvant DNA-cytometry in routine cervical screening: results from 31031 women from the Bonn-region in West Germany.Semantic proximity Read ↗

Comparison of cytology, HPV DNA testing and HPV 16/18 genotyping alone or combined targeting to the more balanced methodology for cervical cancer screening.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.