Article
Head-to-Head Comparison of the RNA-Based Aptima Human Papillomavirus (HPV) Assay and the DNA-Based Hybrid Capture 2 HPV Test in a Routine Screening Population of Women Aged 30 to 60 Years in Germany.
Journal of clinical microbiology - 1 Aug 2015
Iftner Thomas, Becker Sven, Neis Klaus-Joachim, Castanon Alejandra, Iftner Angelika, Holz Barbara, Staebler Annette, Henes Melanie, Rall Katharina, Haedicke Juliane, von Weyhern Claus Hann, Clad Andreas, Brucker Sara, Sasieni Peter
Abstract excerpt
Testing for E6/E7 mRNA in cells infected with high-risk (HR) human papillomavirus (HPV) might improve the specificity of HPV testing for the identification of cervical precancerous lesions. Here we compared the RNA-based Aptima HPV (AHPV) assay (Hologic) and the DNA-based Hybrid Capture 2 (HC2) HPV test (Qiagen) to liquid-based cytology (LBC) for women undergoing routine cervical screening. A total of 10,040...
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