Article
Evaluation of platelet surface glycoproteins in patients with Glanzmann thrombasthenia: Association with bleeding symptoms.
The Indian journal of medical research - 1 May 2017
Mutreja Deepti, Sharma Rahul Kumar, Purohit Abhishek, Aggarwal Mukul, Saxena Renu
Abstract excerpt
BACKGROUND & OBJECTIVES: Glanzmann thrombasthenia (GT) is a rare, inherited autosomal recessive disorder characterized by qualitative or quantitative deficiency of integrin αIIbβ3 [glycoprotein IIb (GPIIb)/IIIa, CD41/CD61] diagnosed by absent or reduced platelet aggregation to physiological agonists, namely, collagen, adenosine-di-phosphate, epinephrine and arachidonic acid. The objective of this study was to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
