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Article

Phasevarion-Regulated Virulence in the Emerging Pediatric Pathogen Kingella kingae

26 Sept 2017

Abstract excerpt

ABSTRACT Kingella kingae is a common etiological agent of pediatric osteoarticular infections. While current research has expanded our understanding of K. kingae pathogenesis, there is a paucity of knowledge about host-pathogen interactions and virulence gene regulation. Many host-adapted bacterial pathogens contain phase variable DNA methyltransferases ( mod genes), which can control expression of a regulon of...

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PMID: 28947652
DOI: 10.1128/iai.00319-17

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