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Article

Ginsenoside Rb1 enhances atherosclerotic plaque stability by skewing macrophages to the M2 phenotype.

Journal of cellular and molecular medicine - 1 Jan 2018

Zhang Xue, Liu Ming-Hao, Qiao Lei, Zhang Xin-Yu, Liu Xiao-Ling, Dong Mei, Dai Hong-Yan, Ni Mei, Luan Xiao-Rong, Guan Jun, Lu Hui-Xia

Abstract excerpt

Atherosclerosis (AS) is characterized as progressive arterial plaque, which is easy to rupture under low stability. Macrophage polarization and inflammation response plays an important role in regulating plaque stability. Ginsenoside Rb1 (Rb1), one of the main active principles of Panax Ginseng, has been found powerful potential in alleviating inflammatory response. However, whether Rb1 could exert protective...

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Identifiers

PMID: 28944992
DOI: 10.1111/jcmm.13329
PMCID: PMC5742675

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STAT6

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