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Article

The Influence of trisomy 21 on facial form and variability

21 Sept 2017

Abstract excerpt

Triplication of chromosome 21 (trisomy 21) results in Down syndrome (DS), the most common live-born human aneuploidy. Individuals with DS have a unique facial appearance that can include form changes and altered variability. Using 3D photogrammatic images, 3D coordinate locations of 20 anatomical landmarks, and Euclidean Distance Matrix Analysis methods, we quantitatively test the hypothesis that children with DS...

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PMID: 28941128
DOI: 10.1002/ajmg.a.38464

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