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Article

Leveraging Population-Based Clinical Quantitative Phenotyping for Drug Repositioning.

CPT: pharmacometrics & systems pharmacology - 1 Feb 2018

Brown Adam S, Rasooly Danielle, Patel Chirag J

Abstract excerpt

Computational drug repositioning methods can scalably nominate approved drugs for new diseases, with reduced risk of unforeseen side effects. The majority of methods eschew individual-level phenotypes despite the promise of biomarker-driven repositioning. In this study, we propose a framework for discovering serendipitous interactions between drugs and routine clinical phenotypes in cross-sectional observational...

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Source

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Identifiers

PMID: 28941007
DOI: 10.1002/psp4.12258
PMCID: PMC5824113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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