Article
Frontotemporal Dementia Caused by the P301L Mutation in the MAPT Gene: Clinicopathological Features of 13 Cases from the Same Geographical Origin in Barcelona, Spain.
Dementia and geriatric cognitive disorders - 1 Jan 2017
Borrego-Écija Sergi, Morgado Joana, Palencia-Madrid Leire, Grau-Rivera Oriol, Reñé Ramón, Hernández Isabel, Almenar Consuelo, Balasa Mircea, Antonell Anna, Molinuevo José Luis, Lladó Albert, Martínez de Pancorbo Marian, Gelpi Ellen, Sánchez-Valle Raquel
Abstract excerpt
BACKGROUND/AIMS: We identified and studied 13 patients carrying the P301L mutation in the MAPT gene from the same area (Baix Llobregat County) in Barcelona, Spain. METHODS: The demographic and clinical features were reviewed retrospectively. Detailed neuropathological characterization was obtained in 9 subjects. To investigate the origin of the P301L mutation in these families, 20 single nucleotide polymorphisms...
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