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Detection of bacterial pathogens from clinical specimens using conventional microbial culture and 16S metagenomics: a comparative study

19 Sept 2017

Abstract excerpt

BACKGROUND: Infectious disease is the leading cause of death worldwide, and diagnosis of polymicrobial and fungal infections is increasingly challenging in the clinical setting. Conventionally, molecular detection is still the best method of species identification in clinical samples. However, the limitations of Sanger sequencing make diagnosis of polymicrobial infections one of the biggest hurdles in treatment....

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PMID: 28927397
DOI: 10.1186/s12879-017-2727-8

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