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Metagenomic analysis of bacterial infections by means of high-throughput DNA sequencing

8 Jul 2011

Abstract excerpt

DNA sequencing technology has undergone a remarkable and continuous improvement in recent years. The so-called 'high-throughput DNA sequencers' can determine hundreds of megabases of DNA sequences per run. We have been applying these new sequencers to the analysis of infectious diseases, especially bacterial infections. We review the efficacy of these sequencers, mainly based on our own experiences. The approach...

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PMID: 21737580
DOI: 10.1258/ebm.2011.010378

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