Article
NLRP3 gene polymorphisms in Iranian patients with recurrent aphthous stomatitis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 2016
Bidoki Alireza Zare, Harsini Sara, Sadr Maryam, Soltani Samaneh, Mohammadzadeh Mahsa, Najafi Shamsolmoulouk, Rezaei Nima
Abstract excerpt
BACKGROUND: Recurrent aphthous stomatitis (RAS) is a common disorder with an unclear etiopathogenesis. Involvement of the immune system in the development of this condition is strongly suggested. As the variations in the inflammasome-related NLRP3 gene have been suggested to affect immune system activity, this case-control study was performed to determine whether these genetic variants are associated with RAS....
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