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Genome‐wide host RNA signatures of infectious diseases: discovery and clinical translation

18 Sept 2017

Abstract excerpt

The use of whole blood gene expression to derive diagnostic biomarkers capable of distinguishing between phenotypically similar diseases holds great promise but remains a challenge. Differential gene expression analysis is used to identify the key genes that undergo changes in expression relative to healthy individuals, as well as to patients with other diseases. These key genes can act as diagnostic, prognostic...

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PMID: 28921535
DOI: 10.1111/imm.12841

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