Article
A molecular perspective of human circadian rhythm disorders.
Brain research. Brain research reviews - 1 Jun 2003
Cermakian Nicolas, Boivin Diane B
Abstract excerpt
A large number of physiological variables display 24-h or circadian rhythms. Genes dedicated to the generation and regulation of physiological circadian rhythms have now been identified in several species, including humans. These clock genes are involved in transcriptional regulatory feedback loops. The mutation of these genes in animals leads to abnormal rhythms or even to arrhythmicity in constant conditions....
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