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Circulating cell-free tumor human papillomavirus DNA is a promising biomarker in cervical cancer

30 Jul 2022

Abstract excerpt

OBJECTIVES: Tumor cells release fragments of their DNA into the circulation, so called cell-free tumor DNA (ctDNA) or liquid biopsy. Here, we analyze if cell-free human papillomavirus DNA (ctHPV DNA) is detectable before, during and after treatment, in patients with cervical cancer or pre-malignant lesions that may develop into cervical cancer, and whether ctHPV DNA levels were correlated to patient or tumor...

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PMID: 35918201
DOI: 10.1016/j.ygyno.2022.07.028

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