Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-Resistance

11 Sept 2017

Abstract excerpt

Many potent antiviral drugs have been developed against HIV-1, and their combined action is usually successful in achieving durable virus suppression in infected individuals. This success is based on two effects: additive or even synergistic virus inhibition and an increase in the genetic threshold for development of drug resistance. More recently, several genetic approaches have been developed to attack the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Innovation and Socioeconomic Development
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28893790
DOI: 10.1128/aac.01486-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-ResistancePMID 28893790Read ↗

A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes All Infectious Provirus in Infected T Cell Cultures.Semantic proximity Read ↗

A combinatorial CRISPR-Cas12a attack on HIV DNASemantic proximity Read ↗

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escapeSemantic proximity Read ↗

CRISPR-Cas based antiviral strategies against HIV-1Semantic proximity Read ↗

CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile?Semantic proximity Read ↗

CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape.Semantic proximity Read ↗

Host Double Strand Break Repair Generates HIV-1 Strains Resistant to CRISPR/Cas9.Semantic proximity Read ↗

A CRISPR-Cas Cure for HIV/AIDSSemantic proximity Read ↗

Elimination of infectious HIV DNA by CRISPR–Cas9Semantic proximity Read ↗

CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape.Semantic proximity Read ↗

Anti-HIV-1 potency of the CRISPR/Cas9 system insufficient to fully inhibit viral replication.Semantic proximity Read ↗

CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.