Article
A new risk locus in CHCHD5 for hypertension and obesity in a Chinese child population: a cohort study.
BMJ open - 11 Sept 2017
Wu Lijun, Gao Liwang, Zhao Xiaoyuan, Zhang Meixian, Wu Jianxin, Mi Jie
Abstract excerpt
OBJECTIVE: Coiled-coil-helix-coiled-coil-helix domain containing 5 (CHCHD5), a mitochondrial protein, is involved in the oxidative folding process in the mitochondrial intermembrane space. A previous study identified a hypertension-related single nucleotide polymorphism (SNP), rs3748024, in CHCHD5 in adults, but there are no reports regarding the association between CHCHD5 and obesity, which is a known risk...
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