Article
Association of IFNG gene polymorphisms with pulmonary tuberculosis but not with spinal tuberculosis in a Chinese Han population.
Microbial pathogenesis - 1 Oct 2017
Li Jiong, Zhou Ying, Zhang Hongqi, He Dan, Zhang Rongmou, Li Yanbing, Guo Chaofeng, Guo Qiang, Wang Longjie, Yang Guanteng, Gao Qile
Abstract excerpt
Spinal tuberculosis (STB) is an extrapulmonary form of tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb), which accounts for around 2% of all TB cases and can lead to spine degeneration. It is widely accepted that host genetic factors participate in the pathogenesis of active TB, but the factors controlling which TB form will manifest after Mtb infection remain unknown. We hypothesized that a genetic...
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