Article
Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin.
Acta diabetologica - 1 Nov 2017
Buchmann Nikolaus, Scholz Markus, Lill Christina M, Burkhardt Ralph, Eckardt Rahel, Norman Kristina, Loeffler Markus, Bertram Lars, Thiery Joachim, Steinhagen-Thiessen Elisabeth, Demuth Ilja
Abstract excerpt
AIMS: Inverse relationships have been described between the largely genetically determined levels of serum/plasma lipoprotein(a) [Lp(a)], type 2 diabetes (T2D) and fasting insulin. Here, we aimed to evaluate the nature of these relationships with respect to causality. METHODS: We tested whether we could replicate the recent negative findings on causality between Lp(a) and T2D by employing the Mendelian...
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