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Article

In search of a physiological function of lipoprotein(a): causality of elevated Lp(a) levels and reduced incidence of type 2 diabetes

1 Jan 2018

Abstract excerpt

“Shallow (wo)men believe in luck or in circumstance. Strong (wo)men believe in cause and effect.”(Ralph Waldo Emerson, The Conduct of Life, 1860). Assigning causality to complex, multifactorial phenotypes, such as incident T2D, is difficult. Assigning causality by the relative lack or an absence of a putative causal mediator is nearly impossible without the benefit of rigorous mechanistic studies and randomized...

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PMID: 29610122
DOI: 10.1194/jlr.c085639

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