Article
Identification of a novel homozygous mutation in transmembrane channel like 1 (TMC1) gene, one of the second-tier hearing loss genes after GJB2 in India.
The Indian journal of medical research - 1 Apr 2017
Singh Pawan Kumar, Ghosh Manju, Sharma Shipra, Shastri Shivaram, Gupta Neerja, Chowdhury Madhumita Roy, Anand Anuranjan, Kabra Madhulika
Abstract excerpt
BACKGROUND & OBJECTIVES: Hearing impairment is a common and heterogeneous sensory disorder in humans. Among about 90 genes, which are known to be associated with hearing impairment, mutations in the GJB2 (gap junction protein beta 2) gene are the most prevalent in individuals with hereditary hearing loss. Contribution of the other deafness-causing genes is relatively poorly understood. Here, we present our...
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