Article
Effect of the RNA pyrophosphohydrolase RppH on envelope integrity in Escherichia coli.
FEMS microbiology letters - 15 Aug 2017
Choi Umji, Park Young-Ha, Kim Yeon-Ran, Seok Yeong-Jae, Lee Chang-Ro
Abstract excerpt
The bacterial enzyme RppH initiates mRNA decay by removing pyrophosphate from 5΄-triphosphorylated mRNA. Escherichia coli RppH has promiscuous substrate specificity, but relatively few transcripts are affected by loss of RppH. The phenotypic analysis of the rppH mutant is required for understanding the physiological role of RppH, but the phenotype of the rppH mutant has not yet been determined. In this study, we...
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