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Article

MicroRNA-142-5p induces cancer stem cell-like properties of cutaneous squamous cell carcinoma via inhibiting PTEN.

Journal of cellular biochemistry - 1 Feb 2018

Bai Xinping, Zhou Yu, Chen Ping, Yang Ming, Xu Jiang

Abstract excerpt

Cutaneous squamous cell carcinoma (cSCC) is a malignancy of keratinocyte-derived skin tumor, which is regarded as the second most common skin cancer worldwide. Accumulating evidence has established that microRNAs (miRNAs) can play a critical role in tumor initiation, progression, and metastasis including cSCC. Abnormal expression of hsa-miR-142-5p has been elaborated in various tumors. Nevertheless, its...

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Identifiers

PMID: 28857248
DOI: 10.1002/jcb.26379

Genes

PTEN

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