Article
Genetic susceptibility to postherniotomy pain. The influence of polymorphisms in the Mu opioid receptor, TNF-α, GRIK3, GCH1, BDNF and CACNA2D2 genes.
Scandinavian journal of pain - 1 Jul 2016
Kalliomäki Maija-Liisa, Sandblom Gabriel, Hallberg Mathias, Grönbladh Alfhild, Gunnarsson Ulf, Gordh Torsten, Ginya Harumi, Nyberg Fred
Abstract excerpt
BACKGROUND AND AIMS: Despite improvements in surgical technique, 5%-8% of patients undergoing herniorrhaphy still suffer from clinically relevant persistent postherniotomy pain. This is a problem at both individual and society levels. The aim of this study was to determine whether or not a single nucleotide polymorphism in a specific gene contributes to the development of persistent pain after surgery. METHODS:...
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