Article
Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.
Translational psychiatry - 29 Aug 2017
Starnawska A, Hansen C S, Sparsø T, Mazin W, Olsen L, Bertalan M, Buil A, Bybjerg-Grauholm J, Bækvad-Hansen M, Hougaard D M, Mortensen P B, Pedersen C B, Nyegaard M, Werge T, Weinsheimer S
Abstract excerpt
Individuals with 22q11.2 deletion syndrome (DS) have an increased risk of comorbid mental disorders including schizophrenia, attention deficit hyperactivity disorder, depression, as well as intellectual disability. Although most 22q11.2 deletion carriers have the long 3-Mb form of the hemizygous deletion, there remains a large variation in the development and progression of psychiatric disorders, which suggests...
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