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Article

An essential role for Tbx15 in the differentiation of brown and "brite" but not white adipocytes.

American journal of physiology. Endocrinology and metabolism - 15 Oct 2012

Gburcik Valentina, Cawthorn William P, Nedergaard Jan, Timmons James A, Cannon Barbara

Abstract excerpt

The transcription factor Tbx15 is expressed predominantly in brown adipose tissue and in those white adipose depots that are capable of giving rise to brown-in-white ("brite"/"beige") adipocytes. Therefore, we have investigated a possible role here of Tbx15 in brown and brite adipocyte differentiation in vitro. Adipocyte precursors were isolated from interscapular and axilliary brown adipose tissues, inguinal...

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Identifiers

PMID: 22912368
DOI: 10.1152/ajpendo.00104.2012

Genes

PGC
PRDM16
UCP1

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