Ribosomal-processing cysteine protease homolog modulates Streptococcus mutans glucan production and interkingdom interactions.

doi:10.1128/jb.00104-24

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Article

Ribosomal-processing cysteine protease homolog modulates Streptococcus mutans glucan production and interkingdom interactions.

Journal of bacteriology - 25 Jul 2024

Treerat Puthayalai, de Mattos Camilla, Burnside Molly, Zhang Hua, Zhu Yanting, Zou Zhengzhong, Anderson David, Wu Hui, Merritt Justin, Kreth Jens

Abstract excerpt

Glucan-dependent biofilm formation is a crucial process in the establishment of Streptococcus mutans as a cariogenic oral microbe. The process of glucan formation has been investigated in great detail, with glycosyltransferases GtfB, GtfC, and GtfD shown to be indispensable for the synthesis of glucans from sucrose. Glucan production can be visualized during biofilm formation through fluorescent labeling, and its...

Topics

Streptococcus mutans
Biofilms
Glucans
Bacterial Proteins
Gene Expression Regulation, Bacterial
Ribosomes
Mutation
Ribosomal Proteins

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Identifiers

PMID: 38899897
DOI: 10.1128/jb.00104-24
PMCID: PMC11270869

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