Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages.

Immunity - 19 Sept 2017

Cambier C J, O'Leary Seónadh M, O'Sullivan Mary P, Keane Joseph, Ramakrishnan Lalita

Abstract excerpt

Mycobacterium tuberculosis (Mtb) enters the host in aerosol droplets deposited in lung alveoli, where the bacteria first encounter lung-resident alveolar macrophages. We studied the earliest mycobacterium-macrophage interactions in the optically transparent zebrafish. First-responding resident macrophages phagocytosed and eradicated infecting mycobacteria, suggesting that to establish a successful infection,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine CCL2
Share to Chemotaxis
Share to Gene Knockout Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycolipids

Share to Inflammation Mediators

Share to Macrophages, Alveolar

Share to Monocytes

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 28844797
DOI: 10.1016/j.immuni.2017.08.003
PMCID: PMC5610147

Genes

CCL2
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages.PMID 28844797Read ↗

Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivitySemantic proximity Read ↗

Playing hide-and-seek with host macrophages through the use of mycobacterial cell envelope phthiocerol dimycocerosates and phenolic glycolipidsSemantic proximity Read ↗

Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant.Semantic proximity Read ↗

Three-dimensional in vivo monitoring of mycobacterial infections and therapeutic efficacy based on tissue-clearing technology CUBICSemantic proximity Read ↗

Early cell-autonomous accumulation of neutral lipids during infection promotes mycobacterial growth.Semantic proximity Read ↗

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipidsSemantic proximity Read ↗

Fit for consumption: zebrafish as a model for tuberculosisSemantic proximity Read ↗

Trisaccharides of Phenolic Glycolipids Confer Advantages to Pathogenic Mycobacteria through Manipulation of Host-Cell Pattern-Recognition ReceptorsSemantic proximity Read ↗

Deciphering and Imaging Pathogenesis and Cording of <em>Mycobacterium abscessus</em> in Zebrafish EmbryosSemantic proximity Read ↗

Modeling Nontuberculous Mycobacterial Disease in <em>Xenopus laevis</em>Semantic proximity Read ↗

<i>Mycobacterium tuberculosis</i> -infected macrophages accumulate more nanoparticlesSemantic proximity Read ↗

Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage MigrationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.