Article
Alterations in plasma triglycerides lipolysis in patients with history of multifactorial chylomicronemia.
Atherosclerosis - 1 Oct 2017
Marmontel Oriane, Di Filippo Mathilde, Marcais Christophe, Nony Séverine, Dumoux Marjorie, Serveaux-Dancer Marine, Caussy Cyrielle, Charrière Sybil, Moulin Philippe
Abstract excerpt
BACKGROUND AND AIMS: The heterogeneity and mechanisms of multifactorial chylomicronemia (MCM) remain poorly understood. To gain new insights, post heparin lipolysis measured at 60 min (PHLA60), in addition to the more commonly used 10 min (PHLA10), was assessed in patients with history of MCM. METHODS: 62 consecutive MCM patients were studied. The evaluation included LPL, APOC2, APOA5, GPIHBP1, LMF1 and APOE gene...
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