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Article

Comprehensive analysis of Chinese patients with non-LPL familial chylomicronemia syndrome: Genetic variants, dietary interventions, and clinical insights.

Journal of clinical lipidology - 1 Jan 2024

Gong Zizhen, Xia Yu, Sun Chengkai, Zheng Wanqi, Du Taozi, Liang Lili, Wang Ruifang, Zhang Kaichuang, Yang Yi, Sun Manqing, Sun Yu, Xiao Bing, Qiu Wenjuan

Abstract excerpt

BACKGROUND: Familial chylomicronemia syndrome (FCS) comprises a group of ultrarare disorders caused by biallelic variants in LPL or, less frequently, by GPIHBP1, APOC2, APOA5, or LMF1. OBJECTIVES: To evaluate the phenotypes and management of eight non-lipoprotein lipase (LPL)-FCS patients. METHODS: Seven pediatric and one adult patients with non-LPL-FCS were enrolled. Clinical features, treatment outcomes, and...

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Source

Identifiers

PMID: 40023655
DOI: 10.1016/j.jacl.2024.07.010

Genes

LPL
GPIHBP1
LMF1
TG
APOA5
APOC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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