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Article

Molecular and Genetic Determinants of Glioma Cell Invasion

4 Dec 2017

Abstract excerpt

A diffusely invasive nature is a major obstacle in treating a malignant brain tumor, "diffuse glioma", which prevents neurooncologists from surgically removing the tumor cells even in combination with chemotherapy and radiation. Recently updated classification of diffuse gliomas based on distinct genetic and epigenetic features has culminated in a multilayered diagnostic approach to combine histologic phenotypes...

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PMID: 29207533
DOI: 10.3390/ijms18122609

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