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Article

Ribosomopathy-like properties of murine and human cancers.

PloS one - 1 Jan 2017

Kulkarni Sucheta, Dolezal James M, Wang Huabo, Jackson Laura, Lu Jie, Frodey Brian P, Dosunmu-Ogunbi Atinuke, Li Youjun, Fromherz Marc, Kang Audry, Santana-Santos Lucas, Benos Panayiotis V, Prochownik Edward V

Abstract excerpt

Ribosomopathies comprise a heterogeneous group of hematologic and developmental disorders, often characterized by bone marrow failure, skeletal and other developmental abnormalities and cancer predisposition. They are associated with mutations and/or haplo-insufficiencies of ribosomal proteins (RPs) and inefficient ribosomal RNA (rRNA) processing. The resulting ribosomal stress induces the canonical...

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PMID: 28820908
DOI: 10.1371/journal.pone.0182705
PMCID: PMC5562309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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