Article
Association of CYP19A1 gene polymorphisms with anoestrus in water buffaloes.
Reproduction, fertility, and development - 1 Mar 2018
El-Bayomi Khairy M, Saleh Ayman A, Awad Ashraf, El-Tarabany Mahmoud S, El-Qaliouby Hadeel S, Afifi Mohamed, El-Komy Shymaa, Essawi Walaa M, Almadaly Essam A, El-Magd Mohammed A
Abstract excerpt
Cytochrome P450 aromatase (encoded by the CYP19A1 gene) regulates oestrogen biosynthesis and so plays an essential role in female fertility. We investigated the genetic association of CYP19A1 with the risk of anoestrus in Egyptian water buffaloes. A total of 651 animals (326 anoestrous and 325 cycling) were used in this case-control study. Using single-strand conformation polymorphisms and sequencing, four single...
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