Gene editing in clinical isolates of Candida parapsilosis using CRISPR/Cas9

Abstract excerpt

Candida parapsilosis is one of the most common causes of candidiasis, particularly in the very young and the very old. Studies of gene function are limited by the lack of a sexual cycle, the diploid genome, and a paucity of molecular tools. We describe here the development of a plasmid-based CRISPR-Cas9 system for gene editing in C. parapsilosis. A major advantage of the system is that it can be used in any...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal resistance and susceptibility
• Share to CRISPR and Genetic Engineering
• Share to Plant tissue culture and regeneration