Article
Third generation EGFR TKIs in EGFR-mutated NSCLC: Where are we now and where are we going.
Critical reviews in oncology/hematology - 1 Sept 2017
Russo A, Franchina T, Ricciardi G R R, Smiroldo V, Picciotto M, Zanghì M, Rolfo C, Adamo V
Abstract excerpt
The therapeutic landscape of Non Small Lung Cancer (NSCLC) has been profoundly changed over the last decade with the clinical introduction of Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) and the discovery of EGFR activating mutations as the major predictive factor to these agents. Despite impressive clinical activity against EGFR-mutated NSCLCs, the benefit seen with 1st and 2nd...
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