Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide regulation of electro-acupuncture on the neural Stat5-loss-induced obese mice.

PloS one - 1 Jan 2017

Fu Shu-Ping, Hong Hao, Lu Sheng-Feng, Hu Chen-Jun, Xu Hou-Xi, Li Qian, Yu Mei-Ling, Ou Chen, Meng Jian-Zhong, Wang Tian-Lin, Hennighausen Lothar, Zhu Bing-Mei

Abstract excerpt

Acupuncture is reported to be effective in treating obesity related illnesses, but its mechanism is still unclear. To investigate this mechanism we applied electro-acupuncture (EA) in a mouse model of obesity and used RNA-seq to identify molecular consequences. Deletion of the transcription factor STAT5 from neurons (Stat5NKO) led to obesity. Acupuncture, in turn, reduced body weight and the ratio of epididymal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue, White
Share to Cold Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Energy Metabolism

Share to Epididymis

Share to Hypothalamus

Share to Mice, Obese

Share to Molecular Sequence Annotation

Share to STAT5 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 28806763
DOI: 10.1371/journal.pone.0181948
PMCID: PMC5555711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide regulation of electro-acupuncture on the neural Stat5-loss-induced obese mice.PMID 28806763Read ↗

Mice harboring the obesity-associated SNP rs1421085 exhibit increased body weight and reveal an IRX3 neuronal circuit regulating body weight.Semantic proximity Read ↗

Chemogenetic targeting TRPV1 in obesity-induced depression: Unveiling therapeutic potential of eicosapentaenoic acid and acupuncture.Semantic proximity Read ↗

Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stressSemantic proximity Read ↗

A Single Bout of Electroacupuncture Remodels Epigenetic and Transcriptional Changes in Adipose Tissue in Polycystic Ovary SyndromeSemantic proximity Read ↗

Electroacupuncture Mimics Exercise-Induced Changes in Skeletal Muscle Gene Expression in Women With Polycystic Ovary SyndromeSemantic proximity Read ↗

The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder.Semantic proximity Read ↗

Identification of leptolin as a novel anti-obesity adipokineSemantic proximity Read ↗

Identification of a Thermogenic Target in the Dorsal Raphe Nucleus for Weight ManagementSemantic proximity Read ↗

In Vivo Reductionist Approach Identifies miR-15a Protecting Mice From ObesitySemantic proximity Read ↗

The Effect of Acupuncture on MiRNA Expression Profiles in the Ovaries of Rats with PCOS and Insulin ResistanceSemantic proximity Read ↗

Mechanisms underlying the efficacy of a rodent model of vertical sleeve gastrectomy — a focus on energy expenditureSemantic proximity Read ↗

Transcriptional and physiological roles for STAT proteins in leptin actionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.