Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells.

doi:10.1016/j.exppara.2017.08.004

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Article

Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells.

Experimental parasitology - 1 Oct 2017

Ribeiro Mayara, Franco Priscila Silva, Lopes-Maria Janice Buiate, Angeloni Mariana Bodini, Barbosa Bellisa de Freitas, Gomes Angelica de Oliveira, Castro Andressa Silva, Silva Rafaela José da, Oliveira Fernanda Chaves de, Milian Iliana Claudia Balga, Martins-Filho Olindo Assis, Ietta Francesca, Mineo José Roberto, Ferro Eloisa Amália Vieira

Abstract excerpt

Trophoblast infection by Toxoplasma gondii plays a pivotal role in the vertical transmission of toxoplasmosis. Here, we investigate whether the antibiotic therapy with azithromycin, spiramycin and sulfadiazine/pyrimethamine are effective to control trophoblast infection by two Brazilian T. gondii genotypes, TgChBrUD1 or TgChBrUD2. Two antibiotic protocols were evaluated, as follow: i) pre-treatment of...

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PMID: 28803905
DOI: 10.1016/j.exppara.2017.08.004

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