Article
Lrp, a global regulator, regulates the virulence of Vibrio vulnificus.
Journal of biomedical science - 11 Aug 2017
Ho Yu-Chi, Hung Feng-Ru, Weng Chao-Hui, Li Wei-Ting, Chuang Tzu-Hung, Liu Tsung-Lin, Lin Ching-Yuan, Lo Chien-Jung, Chen Chun-Liang, Chen Jen-Wei, Hashimoto Masayuki, Hor Lien-I
Abstract excerpt
BACKGROUND: An attenuated mutant (designated NY303) of Vibrio vulnificus, which causes serious wound infection and septicemia in humans, was isolated fortuitously from a clinical strain YJ016. This mutant was defective in cytotoxicity, migration on soft agar and virulence in the mouse. The purpose of this study was to map the mutation in this attenuated mutant and further explore how the gene thus identified is...
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