Article
Heterogeneity of human WT1 gene.
Postepy higieny i medycyny doswiadczalnej (Online) - 11 Jul 2017
Bielińska Ewelina, Matiakowska Karolina, Haus Olga
Abstract excerpt
The WT1 gene, characterized by an extremely complex structure, is located on chromosome 11. It is involved in cell growth and differentiation, and has a strong impact on consecutive stages of the functioning of the body. The WT1 gene may undergo many different mutations, as well as may be overexpressed without a mutation. The molecular basis of diseases such as Wilms tumor, WAGR, Denys-Drash or Frasier syndromes...
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