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Combining Oncolytic Adenovirus with Radiation—A Paradigm for the Future of Radiosensitization

24 Jul 2017

Abstract excerpt

Oncolytic viruses and radiotherapy represent two diverse areas of cancer therapy, utilizing quite different treatment modalities and with non-overlapping cytotoxicity profiles. It is, therefore, an intriguing possibility to consider that oncolytic ("cancer-killing") viruses may act as cancer-selective radiosensitizers, enhancing the therapeutic consequences of radiation treatment on tumors while exerting minimal...

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PMID: 28791251
DOI: 10.3389/fonc.2017.00153

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