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Article

Differential SLC1A2 Promoter Methylation in Bipolar Disorder With or Without Addiction

21 Jul 2017

Abstract excerpt

While downregulation of excitatory amino acid transporter 2 (EAAT2), the main transporter removing glutamate from the synapse, has been recognized in bipolar disorder (BD), the underlying mechanisms of downregulation have not been elucidated. BD is influenced by environmental factors, which may, via epigenetic modulation of gene expression, differentially affect illness presentation. This study thus focused on...

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PMID: 28785205
DOI: 10.3389/fncel.2017.00217

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