The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.

doi:10.1016/j.humpath.2017.07.015

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.

Human pathology - 1 Sept 2017

Marchevsky Alberto M, LeStang Nolwenn, Hiroshima Kenzo, Pelosi Giuseppe, Attanoos Richard, Churg Andrew, Chirieac Lucian, Dacic Sanja, Husain Aliya, Khoor Andras, Klebe Sonja, Lantuejoul Silvie, Roggli Victor, Vignaud Jean-Michel, Weynard Birgit, Sauter Jennifer, Henderson Douglas, Nabeshima Kasuzi, Galateau-Salle Francoise

Abstract excerpt

Immunohistochemistry is used to distinguish sarcomatoid malignant mesotheliomas (SMM) from spindle cell and pleomorphic carcinomas (SPC) but there are no guidelines on how to interpret cases that show overlapping or equivocal immunohistochemical findings. A systematic literature review of the immunophenotype of these lesions was performed and the experience with 587 SMM and 46 SPC at MESOPATH was collected. Data...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diagnosis, Differential

Share to Evidence-Based Medicine

Share to Mesothelioma

Share to Mesothelioma, Malignant

Share to Pleural Neoplasms

Share to Practice Guidelines as Topic

Share to Sarcoma

Source

Open in PubMed

Identifiers

PMID: 28782639
DOI: 10.1016/j.humpath.2017.07.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: evidence-based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.PMID 28782639Read ↗

Molecular and Immunohistochemical Testing in Mesothelioma and Other Mesothelial Lesions.Semantic proximity Read ↗

ALK Positive Histiocytosis Presenting as a Solitary Pulmonary Spindle Cell Tumor Case ReportSemantic proximity Read ↗

Molecular Characterization of Mesothelioma: Impact of Histologic Type and Site of Origin on Molecular LandscapeSemantic proximity Read ↗

Molecular characterization of pleomorphic mesothelioma: a multi-institutional study.Semantic proximity Read ↗

Clinical and molecular characteristics of pulmonary sarcomatoid carcinoma.Semantic proximity Read ↗

Spindle cell and pleomorphic ("sarcomatoid") carcinomas of the lung: an immunohistochemical analysis of 86 cases.Semantic proximity Read ↗

MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data.Semantic proximity Read ↗

Validation of a Gene-Expression Approach for the Cytological Diagnosis of Epithelioid and Biphasic Pleural Mesothelioma on a Consecutive SeriesSemantic proximity Read ↗

Challenges and controversies in the diagnosis of malignant mesothelioma: Part 2. Malignant mesothelioma subtypes, pleural synovial sarcoma, molecular and prognostic aspects of mesothelioma, BAP1, aquaporin-1 and microRNA.Semantic proximity Read ↗

Could spindle cell lung carcinoma be considered and treated as sarcoma, according to its clinical course, morphology, immunophenotype and genetic finding?Semantic proximity Read ↗

[Malignant pleural mesothelioma: 2013 state of the art].Semantic proximity Read ↗

Multiple-marker immunohistochemical phenotypes distinguishing malignant pleural mesothelioma from pulmonary adenocarcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.